News
Events
Research
Ways to help
About us
Contact Us
DONATE NOW
EVENTS
ANNUAL BALL
CONTACT US
SIGN UP TO NEWSLETTER
Feb 2017
Trish Foundation contributes to first-ever discovery
Jun 2017
Researchers funded by the Trish Foundation making great progress
Dec 2017
Announcement by NHMRC
Jan 2018
2018 Round of Funding Four new Projects announced
Jun 2018
Exciting regrowth of nerve fibres
Jun 2018
Dr Merson secures $1 million from NHMRC
Jun 2018
Findings submitted for publication
Jan 2017
New Research Projects commencing 2017 announced

What Role do Natural Killer Cells

play in MS?

 

Investigator:

Dr Fiona McKay, Westmead Institute for Medical Research, NSW

 

Co-Investigators:

Professor David Booth, Westmead Institute for Medical Research, NSW

Associate Professor Golo Ahlenstiel, Westmead Institute for Medical Research, NSW

Professor Steve Vucic, Westmead Institute for Medical Research, NSW

Ms Nicole Fewings, Westmead Institute for Medical Research, NSW

 

Project Grant for three years, 2018 - 2020

Natural killer (NK) cells are responsible for killing harmful cells in the body. This includes the body’s own cells that are infected with viruses, and other immune cells that inappropriately attack our own body (autoimmune cells).

Previous work by Dr Fiona McKay and colleagues has found that in some people with MS, their NK cells are not working properly. In a laboratory model of MS, they have also that malfunction of NK cells are associated with increased MS relapses.

In this Project Grant Dr McKay and her team will determine if NK cells from people with MS are able to kill cells infected with viruses, and/or autoimmune cells, in the laboratory.

A number of drugs that enhance the function of NK cells have been approved to treat cancer. Dr McKay will investigate if these drugs can be repurposed to improve the function of NK cells in people with MS to kill cells infected with viruses, and/or autoimmune cells.

Trish Foundation & MS Research Australia Working together to find a cure for MS
Copyright © Trish Multiple Sclerosis Research Foundation. All rights reserved.