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Feb 2017
Trish Foundation contributes to first-ever discovery
Jun 2017
Researchers funded by the Trish Foundation making great progress
Dec 2017
Announcement by NHMRC
Jan 2018
2018 Round of Funding Four new Projects announced
Jun 2018
Exciting regrowth of nerve fibres
Jun 2018
Dr Merson secures $1 million from NHMRC
Jun 2018
Findings submitted for publication
Jan 2019
New Research Projects commencing 2019 announced

Using MRI to measure MS
severity and progression

 

Postgraduate Scholarship over three years commencing 2019, fully funded by the Trish MS Research Foundation

Investigator:  Dr Justin Garber

The University of Sydney, NSW

Co-investigators:  Professor Michael Barnett, Dr Chenyu Wang

Summary

In this PhD project, Dr Justin Garber and colleagues will use magnetic resonance imaging (MRI) techniques to determine what drives brain cell loss in people with progressive MS. MRI is a powerful technique which can detect subtle changes in the brain and spinal cords of people with MS. Dr Garber will track a group of people with progressive MS over two years and is planning to use advanced MRI techniques to determine whether the majority of brain cell loss occurs within MS lesions in the brain or more generally throughout the brain.

The second part of his study will look at using these MRIs to map the connections in the brain. Comparing changes in these connections over time in people with progressive MS will allow Dr Garber to detect small changes in the brain that occur well before outward signs of disability begin to show. Hopefully, this will provide a simple way of measuring disease activity and could be used in clinical trials to determine whether a treatment is working or not in a shorter timeframe. These markers could provide a framework to help test new myelin repair therapies and ultimately to monitor treatment response in people with MS in clinical practice.

Trish Foundation & MS Research Australia Working together to find a cure for MS
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