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Feb 2017
Trish Foundation contributes to first-ever discovery
Jun 2017
Researchers funded by the Trish Foundation making great progress
Dec 2017
Announcement by NHMRC
Jan 2018
2018 Round of Funding Four new Projects announced
Jun 2018
Exciting regrowth of nerve fibres
Jun 2018
Dr Merson secures $1 million from NHMRC
Jun 2018
Findings submitted for publication
Jan 2019
New Research Projects commencing 2019 announced

Jason Mackenzie onto

MS Genetics


Trish Foundation Postgraduate Research Scholar Jason Mackenzie continues his MS Genetics work in the Genomics Research Centre, Griffith University.  

Jason is interrogating five genomic regions that have been identified as potentially containing MS susceptibility genes.  His approach utilises a comprehensive screening technology and techniques to identify MS-specific gene expression differences.   

Gene expression is the process by which information from a gene is used to make a functional gene product.  By identifying the gene expression differences in MS and non-MS brain and blood tissues, it may be possible to inform the development of new approaches to diagnosis and treatment of MS.  

In the laboratory Jason has undertaken laboratory investigations examining the regions of several sex hormone genes for association with MS within an Australian case-control population.  Within the regions of these sex hormone genes, Jason has examined three markers that have yielded very interesting results that may have implications for People with MS. Further markers are presently being investigated in these sex hormone genes and once completed the results will be swiftly submitted for publication.  

Jason has also been learning from the Director of the Dutch Brain Bank to classify the different lesion types in MS affected brain samples, and interpret the clinical data associated with each sample, subsequently starting work on the brain tissue samples.   

Stemming from this research, Jason has played an important role in sharing new insights from this research with the world by publishing two scientific papers.

Trish Foundation & MS Research Australia Working together to find a cure for MS
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