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Jun 2014
Predicting MS in children
Oct 2014
Three new Incubator Grants announced
Dec 2014
2015 Funding announced
Mar 2015
Investigating new treatment options
Oct 2015
Progress in MS Research Conference
Feb 2016
2016 Round of Funding
Feb 2014
New projects being funded
Feb 2014
Breakthrough study shows great promise

Approved Funding

 

2017 Round of Funding

With our heartfelt gratitude to our very generous Sponsors, donors and supporters, the Trish Foundation is delighted to announce research funding for grants commencing January 2017. These grants were recommended for funding following a thorough review of applications by external peer reviewers and MS Research Australia’s expert Research Management Council.   

The number and quality of applications received continues to grow year on year, making the funding decisions exceptionally challenging. However, the robust procedures ensure that the most rigorous science, with the greatest potential to make an impact for people affected by MS, can keep moving forward.

The Foundation is thrilled to be funding two project grants awarded to outstanding, emerging MS research leaders, Dr Tobias Merson at the Australian Regenerative Medicine Institute, Monash University, Melbourne, and Dr Kaylene Young at the Menzies Institute for Medical Research, Tasmania. These researchers are pursuing exciting and complementary research projects to understand how nerve activity can be used to promote myelin re-growth and restore lost function in MS.

Full details of these two project grants and Dr Joshua Barton’s Postgraduate Research Scholarship, which the Trish Foundation is also funding, can be found on the links below:

Dr Tobias Merson
Dr Kaylene Young
Dr Joshua Barton

Incubator Grant

The Trish Foundation is pleased to announce, with very generous support from guests at the Trish MS Black and White Ball, who are making generous contributions, the following Incubator Grant has been approved for funding:

“Platelet derived microvesicles in Multiple Sclerosis: Characterising the role of platelet alpha granules and P2X7 receptor expression”, the Lay Title being, “Tiny circulating particles may be involved in the acute attack of MS”.

The Incubator Grant has been awarded to Dr Ben Gu, The Florey Institute of Neuroscience & Mental Health, Victoria.  Dr Gu’s Co-Investigators are Professor James Wiley, The Florey Institute of Neuroscience & Mental Health, Victoria, Associate Professor Mark Slee, Flinders University, SA and Ms Malgorzata Krupa, Flinders University, SA.

2016 Round of Funding

The Foundation is pleased to announce the Research Projects which we are funding commencing 2016:  

1.      Dr David Gonsalvez, University of Melbourne, Victoria who is investigating Promoting myelin repair by targeting Wnt signalling. 

The Foundation is honoured to be co-funding this important Research Project with the National Health and Medical Research Council.  Read more.

2.      Dr Steven Petratos, Monash University, Victoria.  Dr Petratos’ Project Grant is titled, “A novel approach to reduce the impact of progressive MS”.

Dr Petratos is the only Australian researcher to receive funding from the International Progressive MS Alliance in their inaugural round of funding. This Project Grant is a continuation of this research. 

The International Progressive MS Alliance is working together to connect resources and experts around the world to find answers and develop solutions to end progressive MS.  MS Research Australia, with whom the Foundation works closely, has joined MS organisations from around the world in a global alliance to end progressive MS.  Coordinated by the MSIF, this Alliance is the most ambitious collaborative project the global MS movement has ever embarked upon.  Read more.

3.      Associate Professor Richard Hughes, University of Melbourne, Victoria.  A/Prof Hughes has been awarded an Incubator Grant titled, “Peptide drugs to treat MS”.  Read more.

4.      Dr Lawrence Ong, The Westmead Institute for Medical Research, who is investigating The role of Vitamin D related genes in MS.  

The Foundation is honoured to be co-funding this important Research Project with the National Health and Medical Research Council.  Read more.

As is always the case, these Projects were recommended for funding by MS Research Australia’s Research Management Council following assessment, evaluation and ranking, including a peer-review process.  The projects were then considered and approved for funding by the Foundation’s honorary Scientific Research Committee and Board of Directors.  

Our heartfelt gratitude to our very generous Sponsors and supporters whose great generosity is enabling us to continue to make a significant contribution to MS research in Australia and also contribute to the world-wide effort.

2015 Round of Funding

The Foundation is pleased to announce the Research Projects which we will be funding commencing 2015:  

1.       Dr Holly Cate – Project Grant.  Enhancing myelin repair by attenuating reactive astrocytes.  Department of Anatomy and Neuroscience, University of Melbourne.  Part funding for two years.

2.       Dr Jessica Fletcher – Fellowship.  Investigating novel molecular events for promoting central nervous system myelination and remyelination.  Department of Anatomy and Neuroscience, University of Melbourne.  Part funding for three years.

3.       Dr Natalie Payne – Incubator Grant.  Transcriptome profiling of neural cells derived from MS patient-specific iPSCs.  Australian Regenerative Medicine Institute, Monash University.  Full funding.

4.      Dr Fiona Mckay – Incubator Grant.  Using MS susceptibility genes to understand the role of EBV in MS pathogenesis.  University of Sydney.  Full funding.

The Projects, as is always the case, were recommended for funding by MS Research Australia’s Research Management Council following assessment, evaluation and ranking, including a peer-review process.  The projects were then considered and approved for funding by the Foundation’s honorary Scientific Research Committee and Board of Directors.  

THANK YOU from the bottom of our hearts to our big-hearted Sponsors and supporters whose tremendous generosity is enabling us to continue making a significant contribution to MS research in Australia.  

Incubator Grants

The Foundation is pleased to announce, with very generous support from guests at The Trish MS Ball 2014 who are making generous contributions, the following Incubator Grant has been approved for funding:

Do MS associated genetic changes in vitamin D metabolism genes affect the function of T-cells? 
Investigators: Professor Heinrich Körner, Menzies Research Institute Tasmania and Professor Bruce Taylor, Menzies Research Institute Tasmania  Read more.

The following Incubator Grants have also been approved for funding:

What is driving neuromyelitis optica?
Investigators: Dr Ben Crossett, University of Sydney and Associate Professor Michael Barnett, University of Sydney  Read more.

Novel drugs from cone snail venom for the treatment of MS
Investigator:  Dr Charles Galea, Monash Institute of Pharmaceutical Sciences  Read more.

2014 Round of Funding  

The Foundation is pleased to announce the Research Projects which we will be funding commencing 2014:  

1. Project Grant:  Professor Trevor Kilpatrick.  Determining how polymorphisms in the MerTK gene modify the risk of multiple sclerosis.  Funding for two years.

2. Project Grant:  Dendritic cell and topical therapies for multiple sclerosis.  A/Prof David Brown.  Part funding for three years.  Read more.

3. Postgraduate Research Scholarship:  Katherine Sanders.  Analyses of epigenetic signatures of post mortem lesions in MS brains and correlation to circulating body fluids.  Funding for three years.  

The Projects were recommended for funding by MS Research Australia’s Research Management Council following assessment, evaluation and ranking, including a peer-review process.  The projects were then considered and approved for funding by the Foundation’s honorary Scientific Research Committee and Board of Directors.  

THANK YOU to our wonderful supporters whose great generosity has enabled us to continue making a significant contribution to MS research in Australia.

2013 Round of Funding

Due to the great generosity of our bighearted supporters, the Foundation is thrilled to announce the following Research Projects will be funded commencing 2013: 

1. Bioinformatics support for research in Multiple Sclerosis - The Australia and New Zealand Multiple Sclerosis Genetics Consortium (ANZGene).  Principal Investigator: A/Prof Jeannette Lechner-Scott, Hunter Medical Research Institute.  The bioinformatician will provide essential statistical analysis for a collaboration of Australian and New Zealand researchers focused on solving multiple sclerosis (MS) via research into the genetics of MS.

2. Part funding – Professor Allan Kermode – Investigating relationships between genetic, infectious and environmental risk factors and their relevance to multiple sclerosis immunopathology

3. Part funding – Professor Michael Pender – CD8 T cell; Epstein-Barr virus; immunity; multiple sclerosis; pathogenesis

4. Jae Lee – Postgraduate Scholarship – Targeting the molecular mechanisms of axonal degeneration and de-remyelination in multiple sclerosis

The four Projects were recommended for funding by MS Research Australia’s Research Management Council following assessment, evaluation, a peer-review process and ranking.  The projects were then considered and approved for funding by the Foundation’s honorary Scientific Research Committee and Board of Directors.

2012 Round of Funding

The Foundation is pleased to announce the following Research Projects will be funded commencing 2012:  

Dr Linda Ly - University of Sydney - Novel regenerative pathways in multiple sclerosis: a proteomic and in-situ analysis of human tissue - Supervisor Dr Michael Barnett. Funding over 3 years

Kasra Taghian - Monash University- Targeting the molecular mechanisms of axonal degeneration in multiple sclerosis - Supervisor Dr Steven Petratos. Grant in 2012

The Projects were recommended for funding by MS Research Australia’s Research Management Council following assessment, evaluation and ranking, including a peer-review process.  The projects were considered and approved for funding by the Foundation’s honorary Scientific Research Committee and Board of Directors.

World first!

The Trish Foundation is providing vital funding to initiate a study into Vitamin D for the prevention of MS.

The Foundation has joined forces with the MS Society Western Australia to kick-start this much-needed MS Research Australia Platform Program.  Read more

2011 Round of Funding  

The Trish Foundation is pleased to report the following Research Projects are being funded in our 2011 round of funding:          

Dr Christopher Siatskas at Monash Immunology and Stem Cells Laboratories Victoria, part funding for three years, his project being titled, “Induction of tolerance to CNS autoantigens”.         

Edwin Lim at University of NSW, part funding for three years, whose project is, “Targeting the kynurenine pathway as a novel therapeutic intervention for MS”.          

Dr Mark Slee at Flinders University & Medical Centre South Australia, his project being, “The Australian and New Zealand NMO Antibody Study”.  

2010 Round of Funding

The following Research Projects are being funded in our 2010 round of funding:

1. Grant - Dr Ben Emery, University of Melbourne. Understanding the events that control myelination in the brain and spinal cord – 2010 and 2011.  Read more

2. Grant - Dr Helmet Butzkueven, Howard Florey Institute. Understanding mechanisms of brain and spinal damage in MS – 2010 and 2011.  Read more

3. Incubator Grant - Dr Fabienne Brilot-Turville, The Children's Hospital Westmead. Biomarkers in early paediatric CNS demyelination, and risk of progression to multiple Sclerosis – 2010.  Read more

2009 Round of Funding

The Trish Foundation is funding the following Research Projects in our 2009 round of funding:

1. Project Grant – 2009 - 2010
Investigators:
Dr Michael Barnett, University of Sydney
Professor Prineas, University of Sydney
Dr Ben Crussett, University of Sydney
Scientific Title: Proteomic and in-situ analysis of multiple sclerosis-specific tissue alterations.
Lay Title: Multiple sclerosis tissue proteomics.

2. Post-graduate Research Scholarship – 2009 - 2011
Investigator: Jason McKenzie, Griffith University
Supervisor: Professor Lyn Griffiths, Griffith University
Scientific Title: Investigation of Gene Expression in Multiple Sclerosis Brain and Blood samples.
Lay Title: Identification of Genes showing Altered Expression in Multiple Sclerosis Brain and Blood Samples.

Dr Barnett, Professor Prineas and Dr Crussett’s Project has generated better than expected preliminary findings and consequently, MS Research Australia’s Research Management Council has approved additional funding for the Project. This has also been approved by the Trish Foundation’s Scientific Research Committee and Board of Directors and the Trish Foundation will fund the additional amount.  Read more.

Trish Foundation’s Research Funds Doubled

The Foundation announced in 2007 the Australian MS Genetics Consortium, known as AusGene had received a special Linkage Grant from the Department of Education, Science and Training and the Australian Research Council (ARC). The Trish Foundation’s contribution of $200,000 was matched, along with the contribution by the John T Reid Charitable Trusts and the research facilitator, MSRA enabling a budget of over A$1million to be established.

Please click here for more information.

MS Brain Bank

The Trish Foundation, firstly underwrote, and then in 2006 provided funds for MS Research Australia’s platform Program the MS Brain Bank to be established. Funds were also provided by the Collier Charitable Fund.  

   

Neurologists Australia-wide agree the MS Brain Bank is vital to finding answers – first the cause and then a cure – for MS. Small brain collections exist throughout Australia but are of limited use. This new centralized MS Brain Bank is establishing one large, manageable resource for all Australian scientists doing advanced MS research.

 

Please click here for more information.

Postgraduate Research Scholarship

The Trish Foundation called for applications, jointly branded with MS Research Australia, for a Postgraduate Research Scholarship commencing 2007. To be eligible for the Trish Foundation Postgraduate Research Scholarship, applications had to be submitted to both MS Research Australia and the National Health & Medical Research Council. The successful applicant for the Postgraduate Research Scholarship was Natalie Payne, the Scientific Title of her Project being, “Stimulation of the innate immune system and its role in generation of CNS autoimmune inflammation”. Natalie Payne’s Project was administered by Professor Claude Bernard, Head, Neuroimmunology Laboratory, Monash Immunology & Stem Cell Laboratories and was completed in 2010.

Betty Cuthbert Fellowship

The National Health & Medical Research Council Betty Cuthbert Awards were launched in November 2005 by the Minister for Health and Ageing, Hon Tony Abbott. The Trish Foundation partly funded the inaugural Betty Cuthbert Fellowship.           

 

 

         

Roy and Carol Langsford, Helmet Butzkueven, Mark Slee, front Betty Cuthbert

Mr Abbott awarded Dr Helmut Butzkueven with the inaugural Betty Cuthbert Fellowship and Dr Mark Slee with the first Betty Cuthbert Scholarship at a ceremony in Canberra. The two new grants from the NH&MRC totalled $355,000 and were jointly funded by MS Research Australia and NH&MRC, with the Fellowship partly funded by the Trish Foundation.

The Betty Cuthbert Fellowship was awarded to Dr Helmut Butzkueven, of the MS Group at the Howard Florey Institute in Melbourne, to continue his research into optic neuritis, the most common presenting symptom of multiple sclerosis.

Please click here for more information. 

Postdoctoral Fellowship

In 2006 the Trish Foundation partly funded a Postdoctoral Fellowship for Dr. D. Linares Bandin (Canberra Hospital, ANU) Supervised by Dr. A. Katsifis and Dr. DO. Willenborg: Novel radiolabelled peripheral benzodiazepine receptor (PBR) ligands for imaging and treating neuroinflammation.

Please click here for Archive information.

Trish Foundation & MS Research Australia Working together to find a cure for MS
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